Researchers used supramolecular nanoparticles to repair the brain’s vascular system and reverse Alzheimer’s in mice. Instead of carrying drugs, the nanoparticles themselves triggered natural clearance of amyloid-β proteins. This restored blood-brain barrier function and reversed memory loss. The results point to a revolutionary new path for treating neurodegenerative diseases.
That article reports that a drug targeted at clearing amyloid proteins didn’t suffice to restore the brain’s waste-clearing functionality; this article reports that a drug targeted at repairing the blood-brain barrier does restore waste-clearing functionality (including amyloid proteins). So they’re not completely contradictory.