Researchers used supramolecular nanoparticles to repair the brain’s vascular system and reverse Alzheimer’s in mice. Instead of carrying drugs, the nanoparticles themselves triggered natural clearance of amyloid-β proteins. This restored blood-brain barrier function and reversed memory loss. The results point to a revolutionary new path for treating neurodegenerative diseases.
“Only 1h after the injection we observed a reduction of 50-60% in Aβ amount inside the brain”
Wow.
Meanwhile, OP posted an article at the same time saying that amyloid proteins don’t actually seem to be related to Alzheimer’s: https://www.sciencedaily.com/releases/2025/11/251111005944.htm
That article reports that a drug targeted at clearing amyloid proteins didn’t suffice to restore the brain’s waste-clearing functionality; this article reports that a drug targeted at repairing the blood-brain barrier does restore waste-clearing functionality (including amyloid proteins). So they’re not completely contradictory.
Different pathways.