A gel injected into the scrotum could be the next male contraceptive::Biotech company Contraline has safely implanted a sperm-blocking hydrogel in 23 men. It’s designed to be a fully reversible vasectomy.
Vaselgel is too cheap to manufacture to get the funding it needs to bring it to market, that’s why they have been trying for 20 years and haven’t succeeded yet. In the US the rights are owned by a non profit Parsemu Foundation formed to fund it. It looks like their private partner NEXT Life Sciences is actually set to come to market with a vaselgel product in 2026 they are calling Plan A.
Interesting marketing choice comparing it to the Plan B pill.
If Plan A works, you don’t need Plan B… 😄
I think that was always the point of the name. this would just be a new plan A.
I thought they were implying something misogynist about women’s ability to plan and how the women’s plan will be considered only if the man’s fails first. Maybe that’s the way to get sex ed to where it’s needed though, “the first anti-woke birth control, putting the control back where it should be.” Wouldn’t be surprised in today’s America. /s
From what I’m reading, they’re not set to go to market; that’s just their goal. Most recent article I found was middle of last year that they had raised more money and were hoping to go to human trials by the end of the year. That aligns with what I remember about Vasalgel from years ago - they had finally made it to monkey trials but their monkey study was not showing a consistent ability to return to virility with the second injection. I seem to remember the proposed reason being that vas deferens in the monkeys/apes they were testing with are actually more delicate than humans’ and so humans should still likely be reversible. Last I heard, I believe they were trying to move forward on the human trial of proving that it works as a contraceptive, to be followed by a human trial showing reversibility. Then radio silence and funding issues. My assumption has always been that they struggled to jump to human trials because of the primate study results hurting the likelihood of reversibility. Hopefully they have reworked it to solve that, or maybe the acquisition and new funding is enough to just push through that regardless and see if humans will be fine.
This kind of thing pops up repeatedly. There’s some big, splashy news about a male contraceptive, and then it flames out, or ends up being vaporware.
The problem is that you need to stop a few million sperm with every single ejaculation; reducing that number by 99% means that you’re still risking pregnancy. Severing the ductus deferens (a vasectomy) means no sperm get through; trying to clip or block them means that some can potentially get through. Hormonal BC has the same issue; while it significantly reduces sperm count, it may not eliminate it entirely. (And there can be some really significant negative side effects from eliminating endogenous testosterone production, since hormonal levels need to be pretty far out of whack before there’s a really big cut in sperm production.)
OTOH, women have to stop two eggs per month, or stop them from being implanted in the uterine wall. A 99% reduction in fertility for women means that it’s very, very unlikely that they’re going to be able to get pregnant.
(Yes, women suffer from hormonal BC as well, but some women need it just to be able to live normal lives. It’s overall less of a problem than it ends up being for men. And women have the option of an IUD as well.)
Personally, I’m in favor of vasectomy; it’s allowed me to avoid having any children for 20-odd years now.
Ive also avoided making kids for the last decade or so but I was born with personality-based contraceptives so I dont know that it counts
Andrew Tate apparently made money selling his, if you want to try it as a business
You are comparing sperm count and egg count as if the amount it an issue. For eggs not to be released, you end up nuking estrogen production. Hormonal BC for women is a lesser evil when comparing it to unwanted pregnancies and health conditions like endo, but you are underestimating just how bad constantly taking the pill for women is.Vasectomy is the way.
Vesectomy is the way if you know for sure that you never want children - they aren’t reversible like birth control are and shouldn’t really be considered reversible at all because there’s a very real risk of them not being so
You are comparing sperm count and egg count as if the amount it an issue
That’s because it is. If you have a 95% reduction in number of eggs, then your odds of pregnancy are very, very low. If you have a 95% drop in sperm count, then it’s still pretty easy for a woman to get pregnant.
Yes, taking hormonal BC is pretty bad for a number of women. OTOH, it’s a life saver for some women, like the ones that have 3.5 week periods. For women that experience adverse side effects from hormonal BC, I’d suggest IUDs. For the very, very small number of women that neither IUDs nor hormonal BC work for, I’d suggest using condoms, and avoiding states run by Republicans.
For men that aren’t sure, I would always suggest vasectomy first, or just learn to be gay (since it a choice, dontcha know, /s). If you end up changing your mind, be a foster parent.
The problem I’ve read with Vasalgel is that they had trouble getting enough voulenteers to test it. Trials are dragging out. It does appear to work otherwise.
I was holding out on it for a while, but ended up getting a vasectomy.
I thought that it, and the vasclips, had both failed in the larger clinical trials at achieving birth control rates that were even on par with hormonal BC. This is what I’m remembering from like seven or either years ago though (and internet search is such garbage now that I don’t know if I could find the sources I’m remembering).; there might be a different formulation now, or something.
From what I understand the problem with Vasagel isn’t it’s efficacy but with the reversibility. You can remove it from the tubes easily but the sperm might not perform as before.
You mean we can’t blame the patriarch for under investment in men’s contraceptives and that it’s actually biology to blame? I’m SHOCKED.
Also, maybe I don’t want a needle stuck into my balls.
Maybe my partner taking oral contraceptive is better to ensure she doesn’t get pregnant.
Also are women supposed to just trust guys, or are they going to protect themselves every time.
Maybe the real reason we don’t have a male oral contraceptive is because the female ones protect the female first and foremost because people suck.
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I gave up on waiting for this tech to become available and just got a vasectomy.
RIP.
It’s not really a big loss in my own personal experience. I kept hearing about reversible male contraceptive technologies “just on the horizon” from my early 20’s and I would have preferred getting a reversible procedure if such a thing had been available sooner, but when I turned age 35 and this tech still hadn’t seen the light of day, I asked myself if it being reversible was really such an important factor. I knew by that point that I never wanted to have any kids, and any future partner I would be with would need to be on the same page as me at a minimum, so I just went ahead and got it done while I was still in my sexual prime so I could enjoy the years I have left.
They are going to need to work on their sales pitch…
Meanwhile, BDSM practitioners are thinking “two birds with one stone (to the nuts)”
Hot sexy babe will inject gel into your scrotum.
It’s the only way I can finish.
These reversable, injectable, male contraceptives have been promised for at least 5 years, when will they come to market?
A lot longer than that unfortunetly
Edit: Found an older link
This isn’t exactly new. Vasalgel offers a similar injection that blocks the tubes, however before then back in the early 2010’s there was also a guy in India testing a better version which did not block the tubes - the compound was polarised, and when the sperm went through it was disoriented such that it couldn’t swim to the egg. The human clinical trials had a 100% success rate at preventing pregnancy, albeit human trials tend not to have that many people (I think there were 26). My understanding is that this became Vasalgel because the pharmacuetical industry didn’t like the fact that it completely avoided the complications that can come with vasectomies where the tube is completely blocked.
I’ve been seeing promises about a new male contraceptive for more than a decade now. They never seem to hit the shelves form some reason.
Probably not a very big market.
I would certainly never use anything more than a condom.
Then hopefully you don’t expect women to take birth control or have an IUD.
A vasectomy in my twenties was the best decision I ever made.
10/10, would snip, tie and burn again.
If something like this had been about I’d have had it done at 21 rather than my wife fucking up her hormones with the pill for a few years before we ended up getting the permanent snip.
Same. 12 years ago, still reaping the benefits.
It’s just so damn expensive
Cheaper than a kid!
Covered by public health care where I am. Just mentioning this as a reminder to look into it wherever you live before assuming it’s expensive.
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£500 well spent. Though I’m still annoyed that my local NHS trust wouldn’t fund it.
For me its something like 2500 in the private hospital because public system doctors will refuse to do it if you are “young” and have no kids
This turns the scrotum into a stress ball.
TSA:what are you hiding sir.
Me:nothing : o.
TSA:(Boink! Boink!)sir stop resisting! This is standard procedure.(Boink! Boink!)
More options are great I suppose, but as a gem-xer I don’t get the modern revolt against the condom. Modern condoms are pretty damn thin / good and are a form of male birth control with bonus of very good disease prevention, have next to no side effects, and minimize messes too.
Modern?
Has it increased in some way over time? I think men not wanting to wear condoms because of how they feel is a tale as old as the condom itself.
I think for those that have grown up with porn in their palms it is different yes. Admittedly that’s my impression and that of my peer group. I’m not aware of data on the matter.
IMO for anyone in a stable monoamorous relationship, the IUD is the superior option, as long as the female partner is a good fit for it and doesn’t have complications from it.
My wife had significant issues with hers, including basically never-ending spotting and occasional surprise periods, cramps, mood issues, etc. She had it removed after 2 years.
I’m thinking a vasectomy is the next thing, but it isn’t covered on my insurance and finding a doctor is intimidating.
There’s no harm in condom + anything else considering all the horror stories of condoms accidentally/intentionally not working.
This gives another option that sounds pretty easy and not very invasive for anyone.
There are horror stories for everything. There are also statistics. If you prefer horror stories to the latter there is nothing you shouldn’t fear.
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Condoms suck for everyone involved
That’s an interesting generalization. I’m going to to count myself out of everyone then.
RISUG has been in promised for what, nearly a decade now? This has been the FSD/Star Citizen of the male contraceptive world, always right around the corner.
Yeah. I got tired of their promises that it’s only a year or two away like 7 years ago.
Is this not the exact same thing as vasalgel? How is this new or different?
Not sure, this seems to be exactly what vasalgel is. At first, I thought the innovation was that they just squirt this stuff into your sack and call it a day, and that would have been different. But nope! Same injection site too. Maybe it’s more effective or something.
Contraline’s method involves making a small piercing in the scrotum and using a handheld injector to push the hydrogel through a catheter that’s connected to the vas deferens. The catheter is then taken out, and the puncture heals on its own.
That sounds like a bit more than just an injection. Not quite like going in for a flu shot to the nuts
bet politicians wont be lining up to regulate and ban this after 15 weeks
