My best friend has struggled with depression for a long time and no SSRI really worked for her. She switched to an SMS medication and it has made a huge difference for her depression.
Meanwhile I’m treated for anxiety moreso than depression, and also felt some emotional blunting on SSRI’s. I switched to an SNRI, which targets both serotonin and norepinephrine and that has gotten a lot better for me. It’s a lot easier for me to feel joy now.
TLDR: if your meds aren’t working for you, shop around and see if something else works better. Yes it takes time, but it’s better than being stuck feeling nothing.
I concurred. I switched from an SSRI to an SMS because of this and other side effects
It’s 2025, at least use RCS
What is an SMS?
https://en.m.wikipedia.org/wiki/Serotonin_modulator_and_stimulator
My best friend has struggled with depression for a long time and no SSRI really worked for her. She switched to an SMS medication and it has made a huge difference for her depression.
Meanwhile I’m treated for anxiety moreso than depression, and also felt some emotional blunting on SSRI’s. I switched to an SNRI, which targets both serotonin and norepinephrine and that has gotten a lot better for me. It’s a lot easier for me to feel joy now.
TLDR: if your meds aren’t working for you, shop around and see if something else works better. Yes it takes time, but it’s better than being stuck feeling nothing.