“Only 1h after the injection we observed a reduction of 50-60% in Aβ amount inside the brain”
Wow.
Meanwhile, OP posted an article at the same time saying that amyloid proteins don’t actually seem to be related to Alzheimer’s: https://www.sciencedaily.com/releases/2025/11/251111005944.htm
That article reports that a drug targeted at clearing amyloid proteins didn’t suffice to restore the brain’s waste-clearing functionality; this article reports that a drug targeted at repairing the blood-brain barrier does restore waste-clearing functionality (including amyloid proteins). So they’re not completely contradictory.
Different pathways.
If this goes to human trials and works and then gets approved for every patient I can only imagine the hundreds of thousands of debt this will put people and their families in. It’s awesome news, but the reality of it sucks
It looks like the research was done by academic and government-sponsored institutions in Spain and China, so hopefully it won’t just become a profit-making tool for the biotech industry.
This will be given to people like Trump. Us poors will not be given this drug.
Let’s give it to Trump tomorrow, before his mind is gone so far that he can’t be held accountable anymore!
So, wait, we figured out how to give mice alzheimers and then cure it? 🤔
I can’t wait to share this news with my friend Charlie. Should I bring flowers?
Mice lie. Monkeys exaggerate. Ferrets are weasels.
Not nice Lie Mice lie.
I normally don’t bother with typos, but this one changes meaning significantly, for those not in the know it’s a saying in biological / biomedical science about the relevance of animal testing results to humans, although I’m unfamiliar with the ferrets part, but it’s cool.
Mice lie and Monkeys exaggerate. - On the use of non-human primates in HIV research, Stephen B Weiner PhD.
Fixed
There’s hope for me yet.
