I suppose it would be mostly practical skills, cooking, fixing things. Usually had to be done by people themselves.
Maybe also mental things like navigating (with or without paper map) and remembering their daily and weekly agendas.
What other things would be a big difference with the people today?
This only works in cities with naming schema that work that way. For my city, if I wanted to go to my old college, I’d drive to Columbia Parkway and have to take Martin Luther King Jr Boulevard all the way in, or divert through downtown to Victory Parkway otherwise. Some places in the city are named logically or you know where they are, but outside of downtown, you abandon the 5th/6th/7th sort of scheme in many cities in America that weren’t initially Planned Cities.
Now, you can do this in a handful of American cities (Indianapolis, for instance), but not most of them.
You can still learn where the streets are. Seattle is one of the worst planned cities in America and you can still navigate it by route if you’ve spent twenty years learning it.